What happens if I overdose on vitamin D? Patient’s cautionary tale

Vitamin D capsules Liquigel spilled from the multivitamin bottle on a flat surfacePublish on Pinterest
Taking nutritional vitamins in portions that exceed the day by day limits can hurt well being. Jeremy Paulowski / Stocksy
  • A brand new research experiences the medical penalties of taking very excessive ranges of vitamin D dietary supplements.
  • The analysis paperwork the story of an individual who took a number of instances the beneficial day by day quantity of vitamin D.
  • The affected person continues to expertise the hostile results of a vitamin D overdose even after discontinuing its use.

A brand new case report offers a stark instance of what can occur if one takes in an excessive amount of vitamin D.

center aged man Referred to hospital by common followAfter experiencing vomiting, nausea, stomach ache, leg cramps, tinnitus, dry mouth, elevated thirst, diarrhea, and weight reduction. The affected person was taking a cocktail of vitamin dietary supplements, together with vitamin D 150,000 IU – the day by day requirement is 10 mcg, or 400 IU.

To place this dose into perspective, the Nationwide Institutes of Well being recommends taking not more than 15 mcg (mcg) per day in dietary supplements. This quantity is the same as 600 worldwide items.

“A standard false impression about vitamin D is that if some is sweet, extra is best,” Dr. Joan Elizabeth MansonMentioned, MD, professor of drugs at Harvard Medical Faculty and chair of the division of preventive medication at Brigham and Girls’s Hospital, who was not concerned within the research, Medical information right now.

This isn’t true, and whereas it is very important keep away from vitamin D deficiency, it’s also vital to keep away from megadoses. In actual fact, megadoses are related to hurt.”

Though the research paperwork an excessive case, Dr. Clifford J. Rosena college scientist and director of the Middle for Medical and Translational Analysis on the Maine Medical Middle Analysis Institute, who was additionally not concerned within the research, stated. MNT Exceeding the beneficial quantities of nutritional vitamins may cause main well being issues.

“The worth of this research is to indicate those that though everybody thinks vitamin D is innocent and the higher — the reality is that extra vitamin D may cause important toxicity even in wholesome people.
– Dr. Clifford J. Rosen

Even after the person stopped taking the complement, his signs persevered, indicating the potential for everlasting harm.

The case report is revealed in BMJ Case Reviews.

The person had been taking greater than 20 prescriptions for 3 months earlier than arriving on the hospital, and his physician referred him.

It’s included in his day by day regime – along with vitamin D – vitamin Ok 2100 mg (day by day requirement 100-300 mcg); Vitamin C and Vitamin B9 (folic acid) 1000 mg (day by day requirement 400 mcg); Vitamin B2 (Riboflavin), Vitamin B6, Omega-3 2000mg Twice Each day (Each day Requirement 200-500mg), Important Issue, Zinc Picolinate, Vitamin B3, Tremendous Advanced 12 1000mcg, Lugol Drops Iodine, Borax Powder, L-lysine powder with NAC (N-acetyl cysteine), wobenzym N, astaxanthin softgel, magnesium malate, magnesium citrate, pure taurine, glycine powder, excessive energy choline (+ inositol), calcium orotate, probiotics, glucosamide and chondroitin advanced, and sodium chloride. The remedy routine was prescribed to him by a dietary therapist.

The preliminary blood check revealed that the affected person introduced blood ranges of vitamin D in extra of 400 nmol/L, which implies he had 8 instances the beneficial quantity of vitamin D in his blood.

The person additionally had an extended historical past of medical issues, together with, “bovine tuberculosisAnd the Left vestibular schwannoma with listening to loss, Hydrocephalus Deal with Ventricular peritoneal shuntbacterial Meningitisand persistent sinusitis. “

vitamin specialist Kristen Kirkpatrickwho was not concerned within the report nor consulted with its topic, advises a extra measured strategy to vitamin D supplementation for her sufferers.

“I like to recommend all of my sufferers discover out about their vitamin D ranges first beforehand, after which work with their physician on the suitable dose if wanted of supplementation based mostly on their ranges and geographic location,” she stated. MNT.

“This case research offers worth as a result of it alerts shoppers to take that step first: Speak to a health care provider, get [vitamin D] estimated ranges.
– Kristen Kirkpatrick, Dietitian

The necessity for vitamin D has been considerably controversial, though the present prevailing consensus is that it’s important for optimum well being.

Our pores and skin produces vitamin D from daylight. A person’s microclimate – and the diploma to which they’re uncovered to the solar – impacts the quantity of vitamin D they produce. The identical applies to pores and skin pigmentation.

Vitamin D Essential For bone well being, calcium absorption and parathyroid assist.

“We’ve got simply revealed a second meta-analysis exhibiting that reasonable day by day doses of vitamin D supplementation cut back superior most cancers incidence and most cancers dying,” stated Dr. Manson.

She continued, “Consuming reasonable doses of vitamin D (2,000 IU day by day) additionally reduces the chance of autoimmune ailments in ladies. crucial [a study Dr. Manson led]. “

“Nonetheless, greater doses of vitamin D should not have these advantages and have additionally been proven to extend the chance of fractures and falls,” Dr. Manson added..

Whereas some have hypothesized that vitamin D deficiency is a danger issue for COVID-19, Dr. Manson famous, “We’ll quickly have outcomes for COVID-19.” Clearwho has been testing vitamin D to forestall extreme COVID and COVID sickness for a very long time, however the jury remains to be out on that.”

“What I talk about most is the affiliation of low ranges of D with issues like temper/psychological well being,” Kirkpatrick stated along with her sufferers.

“Research have proven that vitamin D deficiency can typically be related to, for instance, an elevated danger of melancholy,” she stated.

It additionally discovered that vitamin D can assist deal with infections:

“Irritation is the idea of any actually persistent sickness, together with worsening psychological well being outcomes, and research present that low ranges of vitamin D can result in exacerbation of irritation.

“Most of my sufferers want a complement to assist elevate their ranges,” Kirkpatrick stated. “It’s because the physique is best ready to make use of D which comes from the UV rays of the solar, not from meals.”

Dr. Rosen Hu Amongst those that are usually not satisfied That widespread concern about vitamin D is absolutely justified, describing vitamin D as a “faith.”

97.5% of individuals have sufficient vitamin D; There isn’t any cause to complement until there’s a medical want because of lack of daylight or malabsorption.” MNT.

He additionally asserts, “There isn’t any such factor as a vitamin D deficiency; extreme vitamin D deficiency is the one important class, with ranges under 10 ng/ml.” [nanograms per milliliter]. The beneficial stage of vitamin D is often between 20 and 40 ng/ml.

“The underside line: You will need to keep away from vitamin D deficiency, however moderation is our motto. Extra shouldn’t be essentially higher, and in reality, it may be worse.”
Dr. Joanne Elizabeth Manson

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